The "wise guys" referred to in the title, Harry Valentini (Danny DeVito) and Moe Dickstein (Joe Piscopo), turn out to be not so wise after all in this crime-oriented comedy. Harry and Moe run the risk of certain death when they steal money from a Mafia don (Dan Hedaya) and then try to multiply their ill-gotten gains at the horse races. Naturally, they lose the bundle and the next thing they know they're running from hitmen and trying to come up with enough cash to pay back their debt. Wise Guys' blend of comedy and action represented something of a change of pace for director Brian DePalma, best known for his offbeat thrillers and Hitchcock homages. ~ Eleanor Mannikka, All Movie Guide
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hollybaby21 said "I totally agree. Have you seen the episode in south park, where Bono is the the worlds biggest shit, literally? If not you should check it out it's hilarious. I love how he asks all us working class people to give our money, who struggle to get by, yet you never hear how much cash he gives. He's a total ass wipe."
guitar.dude said "LOL@"politically involved quartet!" Yeah, wasting $40 million on a stage while every other African is dying is SO politically active. Bono is a hypocrite, a dickhead, an illiterate, stupid bully and a shameless fat lie. The other three are worthless as musicians and as human beings but at least they don't pretend to care about anyone or anything but money."